Charlie Bird appeared on the RTE Late Late Show on Friday night ahead of his Croagh Patrick climb on Saturday.
The former RTE reporter spoke to host Ryan Tubridy from Westport in Mayo via video link and delivered a special message to the Irish people using voice technology.
The 72-year-old was diagnosed with Motor Neurone Disease last year after struggling with symptoms that affected his voice.
Using cutting-edge technology, Charlie was able to type his message into an app, which then broadcast the words in Charlie's own voice and accent using voice clips from the RTE archive.
He revealed he will be lighting five candles at the top of the mountain - each for a special cause - and said he hope in the future that April 2 would continue to be a day of celebration.
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Charlie said: "We are all gathered here in Westport for what I believe will be an amazing day not just on Croagh Patrick but in over 200 places around Ireland and in many parts of the world.
"This I hope is going to turn into a national day of celebration. And who am I blaming for this? Yes, you Ryan.
"Ryan, you asked me before Christmas what were my wishes and I said off the top of my head I wanted to climb Croagh Patrick with some of my RTE colleagues.
"What has happened over the past three months has blown me away.
"We have already raised €1million for Pieta House and the Motor Neurone Disease Association, these two charities close to my heart.
"And with Dunnes Stores on board and with the Late Late Show we are going to go way beyond €1 million. I want to say a big thank you to everyone.
"Finally, what I have said before. When I reach the top of Croagh Patrick I am going to light five candles. The first is for one amazing human being, my new pal Vicky Phelan.
"The second one is for everyone who has a terminal illness. The third one is for everyone who is in a dark place and has their own mountains to climb every day.
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"The forth is for everyone who helped out in the great battle against the pandemic. And the last one is for the people of Ukraine who are going through a living hell at the moment.
"And lastly while I am still able I am going to extend the hand of friendship to everyone. I am being uplifted by what is happening right now with Climb With Charlie. And any tears I have are tears of joy."
People took to Twitter to wish him good luck with the climb, saying they were 'moved' hearing him speak again.
One wrote: "Really moving to hear Charlie Bird (in his own voice) on the #latelate. Love the 5 candles. They'll be lighting here too. Best of luck to all climbing their own mountain."
Another said: "Every county in Ireland is behind you @charliebird4"
While one wrote: "I can't be the only one in tears watching Charlie Bird #climbwithcharlie #LateLateShow"
Charlie will begin his Croagh Patrick climb after half nine Saturday morning and it is hoped he will reach the summit shortly after 1pm.
Charlie will climb Croagh Patrick with his friends and family including RTE star Ryan Tubridy, Baz Ashmawy and Donegal crooner Daniel O’Donnell.
Daniel O’Donnell revealed that he will play some songs on his guitar at the top, including one of Charlie's favourites, a Bruce Springsteen track.
The former RTE reporter will then light five candle at the church before making his descent back down the Mayo mountain after 2pm.
Tens of thousands of people will be joining him from all across the country as they are climb their local mountains to support the Climb with Charlie cause.
As many as 212 different climbs with 1,333 various fundraisers across the country will take place as thousands take part in the challenge and they have already raised over €1 million for the Motor Neurone Disease Association and Pieta House.
