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Benzinga
Benzinga
Technology
Vandana Singh

Celsion's Formulated DNA Plasmid COVID-19 Vaccine Candidate Shows Activity Against Two Strains

  • Celsion Corporation (NASDAQ:CLSN) has presented its PLACCINE platform technology at the World Vaccine Congress.
  • "PLACCINE is demonstrating the potential to be a powerful platform that provides for rapid design capability for targeting two or more different variants of a single virus in one vaccine," said Dr. Khursheed Anwer, Chief Science Officer at Celsion. "
  • Dr. Anwer continued, "In the murine model, our multivalent vaccine targeted against two different variants showed to be immunogenic as determined by IgG levels, neutralizing antibodies, and T-cell responses. Additionally, our multivalent vaccine was equally effective against two different variants of the COVID-19 virus while the commercial mRNA vaccine appeared to have lost some activity against the newer variant."
  • Celsion expects results from the ongoing proof-of-concept non-human primate study evaluating the PLACCINE vaccine against the challenge of live SARS-CoV-2 virus in Q2.
  • Durability results will be available in 2H of 2022.
  • PLACCINE is the Company's first-in-class nucleic-acid vaccine platform. It is derived from the Company's TheraPlas platform to develop vaccines against infectious diseases administered by intramuscular injection. 
  • Price Action: CLSN shares are down 3.24% at $3.28 during the market session on the last check Thursday.
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