Bruce Timm says Batman: Caped Crusader gender-flipped The Penguin as Batman had "a lack of good villains" and he wanted more female ones

The Penguin in Batman: Caped Crusader.

One of the biggest talking points surrounding Batman: Caped Crusader was the gender-flipping of The Penguin. 

Often portrayed as a diminutive, gruesome-looking gangster, the villain (voiced by Minnie Driver) was reinvented in the Prime Video animated series as a bawdy, show-stopping cabaret artist moonlighting as the head of a criminal organization.