Bret Michaels suffered a medical emergency and was hospitalised in Nashville just hours before he was due to perform on Thursday night.
The American singer, 59, is said to have suffered a bad reaction to medication related to his diabetes and Covid-19, according to TMZ.
Speaking in a statement shared to social media on Friday morning, Bret apologised to fans for not being able to "rock the stage" and was working on "being back soon".
"To the incredible fans in Nashville, thank you for your well wishes," the update shared across Instagram and Twitter begins.
"I was truly fired up to get on stage in the Music City and perform, but due to an unforeseen medical complication & following hospitalization, it was not possible.
He continues: "I send my deepest apologies for being unable to rock the stage tonight!!! I'm working on being back 100% very soon & hope you rocked hard with my friends Motley/Leppard/Joan & Classless Act."
Bret's hospital trip was announced on stage by Poison bandmates on Thursday night who opted not to perform in light of their colleague's health woes, attendees at the concert in Nashville allege.
The band are currently on a massive stadium tour alongside other legendary acts Motley Crue, Def Leppard and Joan Jett.
Rikki Rockett, Bobby Dall and C.C. DeVille took to the stage to let the crowd how Bret had been hospitalised after a bad reaction to a medication and therefore their set wouldn't be going ahead.
No comment yet about whether the band will be performing at upcoming dating in Florida and Mississippi this weekend.
TMZ has claimed a source close to the star has claimed Bret may have had a bad reaction to medication linked to Covid-19 "that triggered a reaction as a result of his diabetes".
The Mirror has approached representatives for Bret for comment.
Bret was diagnosed with type 1 diabetes at the age of 6, but didn't reveal his condition to fans and the public until 1987 when he collapsed on stage due to low blood sugar.
Speaking to Yahoo Lifestyle in 2019, the Rock of Love star claimed living with diabetes helped prepare him for the challenges he faced in the music industry.
"It helped also to become tougher as I got into the early parts of my career, and the critics were brutal,” he recalled.
"I said, ‘If I can do five injections a day, and every day is a life-and-death struggle at times, I can surely deal with someone throwing some words at me that don’t like me."
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