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The Independent UK
The Independent UK
National
Suha Kidwai

Breakthrough as research finds human brain evolved as two separate systems

  • Stanford University researchers have discovered that the human brain developed as two separate systems that evolved independently before fusing together, rather than growing from a single parent cell.
  • Scientists identified two distinct cell groups during early embryonic development, with one hardwired exclusively to form the front of the brain and the other committed to creating the back.
  • This dual-system structure dates back at least 500 million years and is also found in marine acorn worms, which share a distant common ancestor with humans.
  • The hindbrain governs automatic survival functions such as heart rate and breathing, while the midbrain and forebrain handle complex tasks such as logic, language, and abstract reasoning.
  • The breakthrough allowed scientists to successfully generate human hindbrain motor neurons from stem cells in a lab, which could accelerate research into fatal neurodegenerative diseases such as ALS .

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