A little boy has been found dead and his mother is still missing after a series of devastating tornadoes tore through the Great Plains of the US last night.
Caddo Parish Sheriff's Office confirmed that a "young boy was found deceased" in a "wooded area" of Pecan Farms trailer park near Shreveport in Louisiana.
Cops are still searching for his mother, who is currently listed as missing.
Another victim, an adult male, was rushed to local hospital but the extent of his injuries is unknown.
At a different trailer park in the north of the state, almost 25 people were injured, some critically, when a tornado barreled through and flattened a number of homes.
There were also several reports of trees knocked over and power lines toppled in Union Parish and other areas.
The tornadoes were part of a massive storm system smashing through the Great Plains, with devastating weather conditions confirmed in Texas, Oklahoma and Louisiana.
Five tornadoes were confirmed across north Texas as of Tuesday afternoon based on video and eyewitness reports, but potentially a dozen may have occurred, the National Weather Service in Fort Worth, Texas, reported.
Dozens of homes and businesses were damaged by the line of thunderstorms, and several people were injured in the suburbs and counties stretching north of the Dallas-Fort Worth area.
More than 1,000 flights into and out of area airports were delayed, and over 100 were canceled, according to the tracking service FlightAware.
Two people were missing and homes were destroyed Tuesday when a tornado hit Four Forts, Louisiana, about 10 miles (16 kilometers) from Shreveport, said Sgt. Casey Jones of the Caddo Parish Sheriff's Office.
"I'm hoping they're with family somewhere," Jones said. There were no immediate reports of deaths.
The severe weather threat continued into Wednesday for Louisiana, Mississippi, Alabama and the Florida Panhandle, according to the Storm Prediction Center in Norman, Oklahoma.
Blizzard warnings stretched from Montana into western Nebraska and Colorado, and the National Weather Service said as much as 2 feet (61 centimeters) of snow was possible in some areas of western South Dakota and northwestern Nebraska.
Winds of more than 50 mph (80 kph) at times will make it impossible to see outdoors in Nebraska, officials said.
"There's essentially no one traveling right now," said Justin McCallum, a manager at the Flying J truck stop at Ogallala, Nebraska.
Forecasters expect the storm system to hobble the upper Midwest with ice, rain and snow for days, as well as move into the Northeast and central Appalachians. Residents from West Virginia to Vermont were told to watch out for a possible significant mix of snow, ice and sleet, and the National Weather Service issued a winter storm watch from Wednesday night through Friday afternoon, depending on the timing of the storm.
In the Dallas suburb of Grapevine, police spokesperson Amanda McNew reported five confirmed injuries Tuesday.
A possible tornado blew the roof off the city's service center - a municipal facility - and left pieces of the roof hanging from powerlines, said Trent Kelley, deputy director of Grapevine Parks and Recreation.
It was also trash day, so the storm picked up and scattered garbage all over, he said.
Photos sent by the city showed downed power lines on rain-soaked streets, as well as toppled trees, damaged buildings and a semitrailer that appeared to have been tossed around a parking lot.
In Colorado, all roads were closed in the northeast quadrant of the state. The severe weather in the ranching region could also threaten livestock. Extreme winds can push livestock through fences as they follow the gale's direction, said Jim Santomaso, a northeast representative for the Colorado Cattlemen's Association.
"If this keeps up," said Santomaso, "cattle could drift miles."
A blizzard warning has been issued on Minnesota's north shore, as some areas are expecting up to 24 inches of snow and wind gusts up to 40 mph. And in the south of the state, winds gusting up to 50 mph (80 kph) had reduced visibility.
National Weather Service meteorologist Melissa Dye in the Twin Cities said this is a "long duration event" with snow, ice and rain through Friday night. Minnesota was expecting a lull Wednesday, followed by a second round of snow.
The same weather system dumped heavy snow in the Sierra Nevada and western U.S. in recent days.
Earlier this month, a mum and her eight-year-old son were killed in their sleep after a tornado caused a large pine tree to fall on their home in Alabama in the US.
Chiquita Broadnax, 39, and Cedarrius Tell were sleeping together in the same bed when an EF-2 tornado caused a pine tree to land on their mobile home on Tuesday evening.
Cedarrius' father, Cedric Lamar Tell, who was sleeping in a separate room, was found trapped among the debris.
He was rushed to hospital with critical injuries and underwent surgery but is expected to survive the harrowing ordeal.
The tornado tore apart the neighbourhood on November 29 and left 23 locals injured as the storm ripped across four southern states.
Family member Norman Bennett told WAAY 31 : "The tree fell right slap in the middle of the bed while they were asleep. It fell on the wife and the kid."
She said neighbours had emerged from their homes after hearing dad Cedric screaming in agony.
"He was hollering. 'Find my baby. Find my baby,'' Norman added.
The family's mobile home was next to Flatwood Community Center, which was also crushed by the devastating tornado.