There are a few strategy ripples that flow out from best ball leagues. You're not necessarily throwing out the redraft playbook; however, I believe there are a few differences worth pointing out—just one man's opinion.
First, I'm negating all injury risk. Just look at my 1.01 pick of Panthers RB Christian McCaffrey. He's been as dominant as they come and while I fully appreciate Colts RB Jonathan Taylor, in a pure fantasy foot race, I give the edge to RUN CMC, as the only real concern with him is his ability to stay healthy. However, I do believe you should only carry one RB handcuff in best ball leagues. You're better off in the long run casting a wide net.
Next, stacking is all the rage, but I don't love it. I've ranted—it's a thing I do—about how you don't actually know how the season will play out. It's all a hunch and half of them, at least, are wrong. So stacking, in theory, if Matthew Stafford has a great game, Cooper Kupp will, too. If Russell Wilson has a great game, Courtland Sutton likely did as well. So stacking is when you pair a QB to his WR or TE. In best ball leagues where cash is on the line, there's typically only one prize and that goes to first place. If you really nail your stack, you'll be tough to beat. I believe only certain teams have viable stacking opportunities. For example, I wouldn't stack Mike Evans or Chris Godwin to Tom Brady, because he spreads the ball around. I would consider stacking Patrick Mahomes to Travis Kelce this year, since he's light years ahead of their No. 1 WR. But if your stack doesn't hit, you're toast, so stack at your own risk.
