There are 17 places between Belgium and Wales in FIFA's World rankings but that didn't stop Wales holding Roberto Martinez's side to a 1-1 draw in Cardiff earlier this summer.
A late Brennan Johnson equaliser earned Wales their first Nations League point but they have a mountain to climb if they are to avoid dropping into UNL Group B.
The Dragons are a huge 7/1 with Betway to plunder maximum points from their trip to the King Baudouin Stadium while the hosts are 4/11 to return keep up the pressure on the Netherlands at the top of the section..