The BBC's royal editor has explained why Buckingham Palace's statement about the Queen's health is so serious.
Earlier today, on September 8, the 96-year-old monarch was placed under medical supervision after doctors became concerned for her health. Her immediate family have since travelled to join her at Balmoral, where she is said to be "comfortable and resting."
A statement from Buckingham Palace said: "Following further evaluation this morning The Queen’s doctors are concerned for Her Majesty’s health and have recommended she remain under medical supervision. The Queen remains comfortable and at Balmoral."
READ MORE: Queen Elizabeth placed under medical supervision after doctors' concerns
Prime Minister Liz Truss said "the whole country will be deeply concerned by the news from Buckingham Palace this lunchtime" adding "my thoughts - and the thoughts of people across our United Kingdom - are with Her Majesty The Queen and her family at this time".
The BBC have cancelled all regular programming. Instead, they are running a rolling special news programme running till at least 6pm on Thursday to provide updates on the Queen's condition.
Speaking to BBC One giving an insight into her condition BBC's Royal editor Nicholas Witchell said: "I think this is clearly a very significant moment. For all of the reasons that we have been saying over the last hour or so.
"The fact that the palace, which doesn’t usually comment on the state of her health or the progression of her wellbeing. The fact that it is saying that the doctors are concerned, though they say she remains comfortable at Balmoral.
"The fact that immediate family members are gathering at Balmoral. Prince Charles who is of course staying at the Balmoral estate at Birkhall, he’s traveling over and has been regularly going to see his mother while he’s been staying there. The fact that I think says the most is the fact that Prince William is flying up to Balmoral from the south. So I think, all in all, this is a very sombre moment.
"I think as politicians are saying there is a profound concern. I think it was Nicola Sturgeon who used that phrase and I think that is absolutely right and other politicians echoing that sentiment. Hoping for the best but, let's be completely candid now, braced for the worst."
In a later update on the BBC's rolling news coverage, he described a "deep concern among members of the Royal Family".
He said: "I think we must assume that there are reasons for concern. There has been this gradual deterioration in the Queen's health. Over the past months, there has been no sharp and sudden deterioration. But I think clearly over the past 24 to 48 hours, the doctors have become rather more concerned.
"It comes back to this issue that we were just discussing a moment ago as to whether it is merely this mobility issue, or whether there is and has been something else and you know, I think we can be candid, there have been rumours of cancers but no, of course, confirmation and one wouldn't expect that to be because there is an insistence by members of the royal family which is reflected by royal officials, that these matters are private. It doesn't matter who you are, you are still entitled to private patient confidentiality."
Comments have been turned off for this article but you can leave your tribute to Queen Elizabeth II in this online memorial.
Receive newsletters with the latest news, sport and what's on updates from the Liverpool ECHO by signing up here
READ MORE:
BBC One suspends TV programming to cover updates of Queen's health
Updates as The Queen placed under medical supervision after doctors' concerns
What happens when the Queen dies, and what is Operation London Bridge
How news of Queen's declining health spread suddenly around Parliament
Queen Elizabeth placed under medical supervision after doctors' concerns
Loose Women fans appalled over show's 'silence' on Queen's health