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The Guardian - UK
The Guardian - UK
Science
Tobi Thomas Health and inequalities correspondent

Antidepressants differ in side-effects such as weight gain, UK research finds

Close-up of a female hand holding various pills and capsules of different shapes and colours; the woman's forearm is resting on a long wooden table with dark-stained woodgrain and different pill bottles and blister packs are in the background, blurred.
Researchers found notable variations in the side-effects of different medications. Photograph: Trevor Williams/Getty Images

People taking certain types of antidepressants can gain up to 2kg (4.5lbs) in weight within the first two months of treatment, while patients taking other drugs can lose the equivalent or more, according to a major review of potential side-effects.

The research, led by academics at King’s College London and the University of Oxford, found that while some antidepressants can cause notable changes in body weight, heart rate and blood pressure, others do not cause such physical changes.

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