An anti-vax mum and dad kidnapped their own daughters and fled to South America to avoid them being given Covid jabs.
Interpol are now hunting the parents who vanished with their 10 and 11-year-old daughters.
Clara Magdalena Egler and her older half-sister Lara Valentina Blank have been reported missing.
Clara’s father, Andreas Rainer Egler, and his new wife, Lara’s mother, Anna Maria Egler, fled from their home in Germany.
They are thought to have arrived in Paraguay back on November 27, last year, and are being hunted by the worldwide crime agency, who issued a red alert for the couple, after Clara's mum recently went public about the horrific ordeal.
It is believed the couple are hiding out in an anti-vaxx German settler community in Paraguay.
Clara’s mother, Anna Maja Reiniger-Egler, denounced her ex-husband at a press conference held in the Attorney General’s Office in the Paraguayan capital of Asuncion.
She has desperately appealed to locals to help track the girls down after she went public with her hunt for her daughter.
She said: "We didn't want that. But we finally went public to hope for the support of the people here.
“We want to find them and give them back their old life where they were happy.
"I know after spending so many weeks in this wonderful country that Paraguayans have a big heart.
"Please have a heart for our girls and help us in our search. Thank you very much.
"Clara and Lara surely do not feel very well with this whole situation. It cannot be that they continue the rest of their childhood on the run."
And appealing to her ex-husband, she said: "Andreas, I beg you to end this nightmare. This is not a normal life. Contact us. Girls can't run away all their lives."
She has been joined in her search by Lara's father Filip Blank.
The Paraguayan Trafficking Unit of the Public Ministry and the anti-kidnapping department of the National Police are investigating the case.
Anne's lawyer, Stephan Schultheiss, believes that the couple likely intend to live in an anti-vaccine German settler community in Paraguay.
One such community is called “Paraiso Verde” (Green Paradise) which was started in 2016 but became popular amongst German and Austrian anti-vaxxers fleeing their home country during the pandemic.
However, there are concerns the settlements become hot beds for conspiracy theorists and sometimes outright racist beliefs.
Paraiso Verde itself was founded by an openly anti-immigrant Austrian couple and is reportedly guarded with automatic weapons.
Stephan Schultheiss said: "It is a case of violation of parental authority or kidnapping. Both are wanted by the German courts."
The head of the Surveillance Area of the Coordinator for the Rights of Children and Adolescents (CDIA), Dante Leguizamon, said on Sunday that the couple did not inform the other parent that they intended to go to Paraguay.
They also reportedly sent a farewell letter in which they said that they opposed the girls being vaccinated against COVID-19.
A yellow alert has been issued for the two girls. Yellow alerts are issued in cases including when children are abducted by one of their parents.
During the press conference on Monday, the prosecutor in charge of the case, Karina Sanchez, revealed that the investigation had begun more than five months ago.
She said that they had decided to make the case known at the request of Clara's mother.
Sanchez said that they had managed to locate a home where the girls and the two adult had been living but they fled the property when they realised a search was on.
The authorities have denounced "the secrecy and lack of cooperation of the German communities in the areas where the girls were seen".