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Tuck Seng Wong, Professor of Biomanufacturing, School of Chemical, Materials and Biological Engineering, University of Sheffield

AI-designed viruses are a test of whether biosecurity can keep pace

TSViPhoto/Shutterstock

Scientists have crossed an important line in biological engineering. In a recent study, researchers used artificial intelligence to design complete sets of genetic instructions for bacteriophages, viruses that infect bacteria. Some of those computer-generated designs produced working viruses when they were built and tested in the laboratory.

These viruses were designed to infect bacteria rather than people. The researchers worked with bacteriophages that target E. coli, and one of the AI models they used, Evo 2, was developed with safety restrictions. Its developers excluded viruses that infect organisms such as animals, plants and humans from the data used to train it.

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