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Medical Daily

Health

Elena Vega

A $100 Million Trial Launched Today to Test Whether GLP-1 Drugs Plus Lifestyle Changes Can Prevent Dementia

Dementia United States Alzheimer Association the Alzheimer Association London Clinical Trial Brain Disease

The Alzheimer's Association today launched a $100 million global clinical trial designed to answer one of the most consequential questions in aging medicine: can combining a GLP-1 receptor agonist drug with a proven lifestyle intervention actually prevent dementia?

The trial — named PROTECT-Cog, which stands for Prevention of Risk fOr cogniTive dEcline through Combined Therapy — was announced for the first time today at the Alzheimer's Association International Conference (AAIC) 2026 in London. The conference, running July 12–15, draws nearly 12,000 researchers and health-care professionals from around the world.

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