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Ryan Phillips

49ers Turn to Rookie Starting RB As Christian McCaffrey, Jordan Mason Head to IR

Christian McCaffrey Jordan Mason 49ers Isaac Guerendo Louisville

Isaac Guerendo had four carries for 19 yards and a touchdown against the Buffalo Bulls. | Gregory Fisher-Imagn Images

Isaac Guerendo is ready for his close up.

The San Francisco 49ers made some significant roster moves on Monday, sending their top two running backs to injured reserve. Christian McCaffrey is expected to miss six weeks due to a knee injury, and Jordan Mason is also hitting IR due to an ankle injury. That means a rookie running back is set to take over.

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Mom Who Drove Through Youth Soccer Game, Leaving 2 People Lifeless, Is Released Without Charges

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One subscription that gives you access to news from hundreds of sites

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Macron Ties France's Cost-Of-Living Unrest to Iran War After Trump's 'France Is Burning' Post

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