The 2022 MLB All-Star Game will open with the National League (-115) as a slight favorite over the American League (-105) at Tipico Sportsbook.
Considering the AL has won the Midsummer Classic for eight consecutive years—including six wins at NL ballparks during the streak—there might be some trepidation over backing the home team.
There’s also a new wrinkle this year bettors will want to pay attention to. If the two teams are still tied after nine innings of play, the regular extra innings rules will be eschewed in favor of a Home Run Derby consisting of three players from each side. That could complicate things for bettors who settle on the 1.5 run spread.
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Los Angeles Dodgers legend Clayton Kershaw is starting for the NL while Tampa Bay Rays ace Shane McClanahan gets the nod for the AL with first pitch slated for 8 p.m. ET on FOX.
The AL leads the all-time series, 46-43-2, and leads the all-time run-differential at 378-372.
Let’s run through some of the best bets and make a few predictions. All odds via Tipico Sportsbooks.