More than one billion people have high blood pressure worldwide, and it has become the leading global cause of early death.
But there has been a big unresolved question about the timing of taking blood pressure medication. There have been claims that people should take their medicine at night.
Night-time blood pressure was thought to be a better predictor of cardiovascular outcomes than daytime readings, and there was a suggestion that evening dosing of medication reduced night-time blood pressure to a greater extent.