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The Guardian - UK
The Guardian - UK
Comment
Emma Beddington

Why worry about your body falling apart at 44 or 60 when you could fret about your brain at 58 or 70?

A woman looking at herself in the mirror
‘I swear I used to be young and moderately dewy.’ Photograph: FG Trade/Getty Images

I don’t believe ageing is linear: I reckon we have long plateaux, then everything falls apart all at once. I realised this at the close of my harrowing 31st year, when I looked in the mirror and didn’t recognise the sad, grey ghost staring back. I swear one day I was young and moderately dewy with a functioning musculoskeletal system; the next my face imploded, shortly followed by my knee (yes, it was a fun year). There’s a phrase for this kind of sudden ageing in French: prendre un coup de vieux, which feels appropriate, since I was living in France during that first precipitous decline and prolonged exposure to the angry rigours of Parisian life was at least partly to blame.

Anyway, now science is catching up. Earlier this year, researchers identified two “peaks” for ageing at 44 and 60, and now a new paper points to three peaks in brain ageing. At 58, there are changes in proteins associated with wound healing, metabolism and mental health; at 70, it’s age-related brain conditions; and when we hit 78, immunity and inflammation-associated proteins are affected.

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