
Gainers
- PepGen Inc. (NASDAQ:PEPG) jumped 110.2% to close at $10.93 after the company announced results from its Phase 1 healthy volunteer trial of PGN-EDO51 for Duchenne Muscular Dystrophy. The trial met its primary endpoint.
- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) shares rose 103.8% to close at $9.58 after Biogen and Eisai announced their Phase 3 Clarity study of lecanemab met its primary endpoint.
- Prothena Corporation plc (NASDAQ:PRTA) shares jumped 87.5% to close at $58.00 on Wednesday after Biogen and Eisai Co. Ltd. announced late Tuesday positive results from a late-stage study of their Alzheimer’s treatment candidate. Prothena is a biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating rare neurodegenerative diseases, like Alzheimer’s.
- SOBR Safe, Inc. (NASDAQ:SOBR) climbed 83% to close at $2.47 after the company announced its SOBRcheck is replacing breathalyzers in the American judicial system.
- BTRS Holdings Inc. (NASDAQ:BTRS) gained 60.8% to close at $9.28. The EQT X fund agreed to acquire BTRS Holdings, a B2B accounts receivable automation and integrated payments company, in an all-cash transaction valuing Billtrust's equity at $1.7 billion.
- FingerMotion, Inc. (NASDAQ:FNGR) gained 58.9% to close at $1.70.
- Biogen Inc. (NASDAQ:BIIB) shares rose 39.9% to close at $276.61. Biogen and Eisai Co. announced late Tuesday positive results from a late-stage study of their Alzheimer’s treatment candidate.
- bioAffinity Technologies, Inc. (NASDAQ:BIAF) rose 37.7% to close at $2.92 after the company announced it received an additional $7.7 million from the exercise of warrants.
- Missfresh Limited (NASDAQ:MF) gained 34.9% to close at $0.1160.
- KLX Energy Services Holdings, Inc. (NASDAQ:KLXE) climbed 30.3% to close at $6.97. KLX Energy Services raised Q3 sequential revenue growth from 9%-13% to 16%-18% and adjusted EBITDA from 10%-12% to 14%-16%.
- Top Ships Inc. (NASDAQ:TOPS) gained 29.5% to close at $3.03 after the company announced 1H FY22 revenue of $38.8 million, which is up 53% year over year.
- Quanterix Corporation (NASDAQ:QTRX) gained 29.2% to close at $10.41.
- HeartBeam, Inc. (NASDAQ:BEAT) jumped 27.9% to close at $3.44. HeartBeam was granted patent for signal transformation from vector electrocardiogram to 12-lead electrocardiogram.
- Iveda Solutions, Inc. (NASDAQ:IVDA) rose 24.2% to close at $0.67.
- Blue Apron Holdings, Inc. (NYSE:APRN) jumped 24% to settle at $6.21 on above-average volume amid retail investor interest.
- AC Immune SA (NASDAQ:ACIU) gained 23.8% to close at $3.12. Shares of companies with Alzheimer's programs traded higher after Biogen and Eisai announced their Phase 3 Clarity study of lecanemab met its primary endpoint.
- MorphoSys AG (NASDAQ:MOR) rose 23.4% to settle at $5.49.
- ProMIS Neurosciences, Inc. (NASDAQ:PMN) rose 23.2% to close at $6.15.
- Owlet, Inc. (NYSE:OWLT) gained 22.9% to close at $1.29. Owlet, last month, posted a Q2 loss of $0.16 per share.
- Senmiao Technology Limited (NASDAQ:AIHS) rose 22.2% to close at $1.02.
- Neuronetics, Inc. (NASDAQ:STIM) climbed 21.9% to close at $2.90.
- Nano-X Imaging Ltd. (NASDAQ:NNOX) climbed 21.2% to close at $12.33. Nano X Imaging, last month, posted a Q2 loss of $0.16 per share.
- Spruce Biosciences, Inc. (NASDAQ:SPRB) jumped 21% to settle at $1.44. Spruce Biosciences, last month, posted a Q2 loss of $0.51 per share.
- Ginkgo Bioworks Holdings, Inc. (NYSE:DNA) gained 20.1% to close at $3.47.
- Aspen Group, Inc. (NASDAQ:ASPU) gained 19.7% to close at $0.3947. Aspen Group Director Douglas Kass acquired a total of 61,500 shares at an average price of $0.42.
- Aura Biosciences, Inc. (NASDAQ:AURA) gained 19.2% to settle at $18.35. Aura Biosciences said first patient was dosed in Phase 1 study evaluating belzupacap sarotalocan (AU-011) for the treatment of non-muscle invasive bladder cancer.
- Heliogen, Inc. (NYSE:HLGN) climbed 19.2% to settle at $2.05.
- Denali Therapeutics Inc. (NASDAQ:DNLI) gained 17.7% to close at $32.12.
- Workiva Inc. (NYSE:WK) jumped 17.6% to close at $76.15. Workiva is said to draw Thoma Bravo, TPG interest, Bloomberg reported.
- Sonder Holdings Inc. (NASDAQ:SOND) gained 16.8% to close at $1.80.
- Processa Pharmaceuticals, Inc. (NASDAQ:PCSA) surged 16.2% to settle at $2.22.
- RadNet, Inc. (NASDAQ:RDNT) gained 16.1% to close at $21.13.
- Equinox Gold Corp. (NYSE:EQX) jumped 16% to settle at $3.56.
- Atara Biotherapeutics, Inc. (NASDAQ:ATRA) gained 15.3% to close at $3.84. Atara Biotherapeutics will receive additional near-term milestone payment under updated tabelecleucel commercialization agreement with Pierre Fabre.
- Coeur Mining, Inc. (NYSE:CDE) jumped 15.2% to close at $3.26.
- New Gold Inc. (NYSE:NGD) gained 13.5% to close at $0.84.
- Peabody Energy Corporation (NYSE:BTU) gained 11.6% to close at $24.85.
- Pacific Biosciences of California, Inc. (NASDAQ:PACB) rose 11.4% to close at $5.85.
- Invitae Corporation (NYSE:NVTA) gained 11% to close at $2.62.
- Yamana Gold Inc. (NYSE:AUY) gained 10% to close at $4.41.
- Lilly and Company (NYSE:LLY) rose 7.5% to close at $334.38. Shares of companies with potential Alzheimer's treatments traded higher in sympathy with Biogen.
- Janux Therapeutics, Inc. (NASDAQ:JANX) gained 6.3% to close at $13.60.