
Small businesses are the backbone of the U.S. economy, but not every city is a safe bet for entrepreneurs. Some places see more small business failures than others, and knowing where these struggles happen can help you avoid common mistakes. If you’re thinking about starting a business or already running one, understanding these trends matters. It can help you plan better, spot risks early, and make smarter decisions. This list ranks the cities where small businesses are failing the most, and it offers practical advice for anyone hoping to beat the odds.