Liz Truss has been ordered to "come out of hiding" after sparking chaos in the markets with her disastrous mini-budget.
The Prime Minister has been in office for less than a month and is already facing the prospect of a humiliating U-turn over her financial plan.
Conservative MPs are said to be furious with Mrs Truss over her mini-budget "gamble" amid fears she will "crash the economy".
Some Tories have already submitted letters of no confidence in the new PM.
Instead of defending her deeply unpopular plan, Mrs Truss has been missing in action since her Chancellor Kwasi Kwarteng delivered the Government's mini-budget in the Commons on Friday.
She is finally breaking her silence this Friday morning with a frenetic round of BBC interviews - one week after the mini-Budget.
Scottish First Minister Nicola Sturgeon asked on Thursday "where even is the PM?"
Keith Brown, deputy leader of the Scottish National Party, added: “As the pound continues to plummet, Britain’s hopeless Prime Minister seems to have disappeared without trace.
“It is astounding that Liz Truss has not made a single public appearance or statement since last Friday.
"It is time for her to come out of hiding and at least make the pretence of leading the country through this self-inflicted crisis.”
Mrs Truss has not spoken in public since she delivered a speech at the UN a week ago.
Her address at the General Assembly took place during the "graveyard slot" and largely went unnoticed.
She has been missing in action since Mr Kwarteng's speech in Parliament on Friday.
However, she came out of hiding on Thursday when photographers spotted her leaving Downing Street for her morning run.
Since her mini-budget was announced, the pound has crashed to a record low against the dollar.
Meanwhile, Labour is soaring ahead in the polls, with Sir Keir Starmer's party holding a 17-point lead over the Tories. A YouGov poll on Thursday gave Labour a 17-point lead over the Tories on ‘delivering economic growth’ and a 32-point lead on ‘tackling the cost of living’.
In a barnstorming speech at conference, Sir Keir said: "As in 1945, 1964, 1997, this is a Labour moment."
He slammed the PM's mini-budget for benefiting the "top 1 percent", while posing the "biggest hit to living standards in a century".
Amid the ongoing chaos in the markets, Sir Keir has now urged the Government to cancel the party conference recess - due to last until October 11 - and abandon last week's mini-Budget "before any more damage is done".
Pressed on how quickly, Sir Keir said: "As soon as possible - tomorrow."
As Labour grows in strength, divisions are emerging in the Tory party.
Some Tories are eyeing up the prospect of another leadership race, with letters of no confidence already submitted.
Tory ex-Chancellor Ken Clarke said Liz Truss and Kwasi Kwarteng “have made a catastrophic start” and the mini budget must be “torn up”.
“I’ve never known a budget cause a financial crisis immediately like this,” he told Sky News. “The budget was a serious mistake and it has caused a serious problem.”
He said the budget was based on “naive” thinking and “I hope that’s all been torn up and they’re now sitting down and listening to the Treasury, the Bank of England and those serious economists who I’m sure are happy to give them proper advice.”
But he said Kwasi Kwarteng should not resign, adding: “We can’t keep having a different chancellor every other week”.
Tory former Cabinet minister Julian Smith said Kwasi Kwarteng and Liz Truss must tear up part of their mini-Budget.
Conservative MP Simon Hoare said: "In the words of Norman Lamont on Black Wednesday: 'today has been a very difficult day'."
He added: "These are not circumstances beyond the control of Govt/Treasury. They were authored there. This inept madness cannot go".
Mel Stride, the Conservative chairman of the Commons Treasury Committee, warned "there's a lot of concern within the parliamentary party, there's no doubt about that".
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One Tory source told the Mirror: “It’s bizarre. I’m getting dozens of emails from my own constituents saying they do not think they can vote for our party because of this mini-budget."
Another Tory MP told Sky: "Liz is f*****... You cannot have monetary policy and fiscal policy at loggerheads. Something has to give... They are already putting letters in as [they] think she will crash the economy."
A different Conservative MP told the Guardian: "Early in the New Year, if intermediate outcomes fail to suggest Truss’s project is working, she’s going to have to do something – that could be throwing Kwasi to the wolves, or else my colleagues will take some sort of action."
Tory MP Robert Largan said he had "serious reservations" about the mini-budget and that cutting the 45% tax rate for those earning over £150,000 was "a mistake".
Torsten Bell, chief executive of the Resolution Foundation think tank, warned “this is by far the worst unforced economic policy error of my lifetime”.
He tweeted: “The scale of the destruction it is bringing is hard to comprehend: higher import prices, surging mortgage bills, higher deficits risking big spending cuts to come, pension funds taking big losses on forced asset sales, likely lasting risk premiums for UK firms and govt.”
Theresa May's former chief of staff in No 10 Nick Timothy also attacked the government's plan.
"This is not conservatism," he tweeted.
"And it is not what conservatives do. Ideology and unnecessary risks with market confidence are supposed to be what the other side does.
"We do need a different plan - but this is a disaster that should never have happened."
Some are also calling for Mr Kwarteng to resign.
TSSA union General Secretary Manuel Cortes said: "Along with Truss the Chancellor must resign without delay and if they refuse to do so Tory MPs must remove them.
"No one can be in any doubt that their bogus economic strategy is a real and present danger to British jobs, businesses and livelihoods.
“They have done the impossible - uniting the financial markets and trade unions."
However, a government source said Mr Kwarteng had no plans to resign or reverse his tax cuts despite chaos on the markets.
And Mrs Truss is refusing to sack her Chancellor.
A No10 spokesman said: "The PM and the Chancellor are working on the supply side reforms needed to grow the economy which will be announced in the coming weeks.”
The Chancellor failed to appear before the media on Thursday despite three days of silence - including when he was awkwardly followed by a camera crew on Monday.
A Downing Street source indicated Mrs Truss would not appear publicly on Thursday either - and confirmed there were no plans for her to recall Parliament. But she was doing BBC interviews on Friday.
Reports suggest ‘big beast’ Tory MPs will swerve this weekend’s Tory party conference including ex-Chancellor Rishi Sunak and Treasury Committee chairman Mel Stride.
Mr Kwarteng is currently billed to deliver his big speech on Monday afternoon. It is in a section titled: ‘Delivering a growing economy’.
Timeline of events
- Friday September 23 - Chancellor Kwasi Kwarteng delivers his mini-budget in the House of Commons, announcing the biggest package of tax cuts in 50 years
- Friday September 23 - The pound slumps against the dollar immediately after Mr Kwarteng's announcement
- Monday September 26 - Sterling hits an all-time low against the dollar
- Monday September 26 - The Bank of England says it is monitoring developments "very closely" and "will not hesitate to change interest rates" if necessary
- Tuesday September 27 - The International Monetary Fund (IMF) urges Mr Kwarteng to "re-evaluate the tax measures"
- Wednesday September 28 - The Bank of England pledges to buy £65 billion of UK bonds to stabilise the market
