England will be hoping to avenge their defeat at the hands of South Africa in 2019's World Cup final with what will be their last chance to face the world champions before the 2023 tournament begins in France next September.
Eddie Jones's side have had a mixed Autumn Nations Series campaign, with a defeat against Argentina followed up by a win against Japan and a dramatic draw with New Zealand last weekend which saw the Red Rose overturn a 25-6 deficit in the final ten minutes at Twickenham.
Now they will face one of the best teams in the world, hoping that they can avenge their defeat against the Springboks in the 2019 World Cup Final. They defeated South Africa 27-26 last November, with a last gasp kick from Marcus Smith sealing the win for the hosts.
England have made four changes for the test, with Ellis Genge dropped to the bench as Mako Vunipola takes his place alongside Saracens teammate Jamie George comes in for Luke Cowan-Dickie. Northampton winger Tommy Freeman also starts in place of Jack Nowell with clubmate Alex Coles coming into the pack.
Here is all the information you will need ahead of England vs South Africa.
When is England vs South Africa?
The fixture between England and South Africa takes place at Twickenham Stadium in London on Saturday, November 26 and kicks off at 5:30pm (GMT).
How can I watch England vs South Africa?
The match will not be available on terrestrial television and like the rest of the Autumn Internationals will be broadcast on Amazon Prime.
Prime members in UK (England, Scotland, Wales and Northern Ireland) and Ireland can watch the 2022 Rugby Autumn Nation series on Prime Video for no additional fees.
Non-Prime members can start a 30-day free trial of Prime (£8.99/month or £95/year), or Prime Video subscription (£5.99/month).
England team vs South Africa:
England: Steward; Freeman, Tuilagi, Farrell (capt), May; Smith, Van Poortvliet; M Vunipola, George, Sinckler, Itoje, Hill, Coles, Curry, B Vunipola.
Replacements: Cowan-Dickie, Genge, Stuart, Ribbans, Simmonds, Youngs, Slade, Nowell.