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Rob Poole, Professor of Social Psychiatry, Bangor University

What long-term opioid use does to your body and brain

Matthew Perry’s colon ruptured as a result of his opioid use. Reuters/Alamy

In his new autobiography, Matthew Perry reveals that his colon burst as a result of his addiction to opioid painkillers. The 53-year-old actor, who played Chandler Bing in Friends, was in a coma for two weeks following the incident and had to wear a colostomy bag for nine months.

Many people take prescription opioids, such as codeine and hydrocodone, to manage pain, so this news may be quite alarming. But can prescription opioids really cause your colon to burst?

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