
Polynucleotides are one of the most exciting new developments in skin injectables. They differ from filler or skin boosters (which are hyaluronic acid-based formulas that physically plump up the skin), in that they act as a ‘biostimulant’, boosting the fibroblast cells in the body, and therefore collagen and elastin, without adding any volume.
The treatment has been making headlines of late, not least because of the attention-grabbing science behind them. Polynucleotides (which are quite literally multiple chains of nucleotides, the building blocks of DNA) are derived from salmon sperm, as they most closely mimic our own. After being extracted from the gonads, the salmon DNA is then distilled, purified and mixed into a water formula, before injection. It can be used on the face, neck, and hands. But perhaps its most popular use is for under the eyes. And, I found out exactly why, when I tried the treatment at 111 Harley St. a few months ago.