
A new umbrella review challenging long-held public beliefs about the cause of depression has caused a stir in the psychiatric community but it has not advised people to quit their antidepressant treatments.
The Serotonin Theory of Depression: A Systematic Umbrella Review of the Evidence was published in the journal Molecular Psychiatry, and found that after reviewing a collection of previously published studies examining the connection between serotonin levels and depression there was little evidence to support the established idea that chemical imbalances were the cause.