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The Independent UK
The Independent UK
National
Graig Graziosi

What a new study on depression does – and does not – tell us about antidepressants and serotonin

Shutterstock/callumrc

A new umbrella review challenging long-held public beliefs about the cause of depression has caused a stir in the psychiatric community but it has not advised people to quit their antidepressant treatments.

The Serotonin Theory of Depression: A Systematic Umbrella Review of the Evidence was published in the journal Molecular Psychiatry, and found that after reviewing a collection of previously published studies examining the connection between serotonin levels and depression there was little evidence to support the established idea that chemical imbalances were the cause.

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