Russian beer has been pulled from the fridges at every branch of Wetherspoon across the country.
Bottles of Baltika Lager - brewed in Vladimir Putin's home city of St Petersburg - have been removed from sale.
A Wetherspoon spokesman said: "In light of the situation in Ukraine we just felt that we could not stock it anymore. As of today all those beers won't be available in any Wetherspoon pub and either have been or are in the process of being returned to the Carlsberg distributor.
"We are not implying in any way that anyone involved with the brewery is directly involved with what's going on but we thought in light of the current situation our pubs don't want to be serving Russian beers."
Wetherspoon also sells Smirnoff vodka, which is owned by London firm Diageo and produced in different distilleries around the world.
Nightcap group, which owns venues The Cocktail Club, Tonight Josephine and Barrio Familia, has paused all sales of vodka in its 25 bars.
Well-known CompareTheMarket adverts featuring meerkats with Russian accents are being pulled from TV news programming due to the war.
Cosmetics chain Lush has said it will close its 15 stores in Ukraine due to the invasion.
Lush chief executive Mark Contantine said all his staff in the country were safe, but that closing the stores was a necessary precaution.
Lush has six stores in Kyiv, the Ukranian capital. It also has two in major city Lviv, three in Odesa, two in Kharkiv and one in Zaporizhzhia.
The firm is trying to get its products to Ukranians to help them during the invasion.
