Maxwel Cornet is unlikely to feature against RSC Anderlecht on Thursday night after missing training on Wednesday.
The summer signing from Burnley picked up a calf injury in West Ham United's 2-0 win over Wolves on Saturday and is a doubt to be fit for the UEFA Europa Conference League fixture.
David Moyes ran his players through some light drills in an open training session on Wednesday morning before travelling to Belgium and Cornet was absent from the group.
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While it is unknown how long the Ivorian will be sidelined for, he is all but certain to miss the group stage game against the Belgian side.
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Speaking about Cornet after the Wolves game, Moyes said: "He felt his calf, so that was it. I’ve not had the chance to speak to the medical team yet, I’m not saying it’s a calf strain but it looks like something to do with his calf."
Meanwhile, Jarrod Bowen, took part in open training with his fingers taped together after picking up an injury to his finger against Wolves.
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