We're heading into Week 6, and two teams will be on bye: the Steelers and Packers.
Additionally, we are keeping our eye on some pretty big injuries. Anthony Richardson and Daniel Jones could miss time with injury, so those in two-QB leagues should pick up some insurance. James Conner and Justin Jefferson also left their games with injuries, and those will be big holes to fill if they can't return sooner than later. Running Back Khalil Herbert will miss multiple weeks with a high ankle sprain.
Be sure you check your waiver wire even if you don't need an immediate replacement for this week. A player such as K.J. Osborn or Quentin Johnston could have been dropped as fantasy managers had to cover bye week absences in Week 5.