‘We were sitting with our calculator saying “we can afford that!”’ Joy for families as cystic fibrosis drug prices fall within reach

Cystic fibrosis patient Kayla Krumrey with the Trikafta (also known as Kaftrio) she takes to treat her condition. Photograph: St Louis Post-Dispatch/TNS/Getty Images

Seven-year-old Grant Leitch had an important question for his mother. He asked if his little brother, Brett, who has cystic fibrosis (CF), was going to die.

The South African family, like tens of thousands around the world, have been priced out of access to modern cystic fibrosis therapies, and if Grant had asked at the start of 2025, he might have received a less optimistic answer.