Warren Gatland has torn up his forwards pack as he made five personnel changes from the side that lost to Ireland, with Alun Wyn Jones and Justin Tipuric left out completely.
Taulupe Faletau drops to the bench, as Gatland opts for a back-row of Christ Tshiunza, Tommy Reffell and Jac Morgan, with the first two in line for their first Six Nations starts.
Despite former captain Jones being confirmed as fit earlier this week, Dafydd Jenkins comes into the starting side to partner Adam Beard in the second-row, while Rhys Davies is preferred to his Ospreys team-mate on the bench.
