US stocks have delivered strong returns in 2026, with at least 10 companies valued at more than $5 billion seeing their share prices more than triple this year. Healthcare and technology stocks have dominated the list of biggest winners, with gains ranging from 234% to 734%, according to market data.
Biotechnology company Moderna leads the rankings, followed by flash memory maker SanDisk and cancer treatment developer Iovance Biotherapeutics. Seven of the 10 biggest gainers belong to the healthcare sector, while the remaining three are technology companies.