Two independent studies published in June 2026 confirm that the 2025–2026 updated COVID-19 vaccine continues to provide meaningful protection against severe disease — even in a population with high prior immunity from both previous vaccines and previous infections.
According to CIDRAP reporting on June 23, 2026, a study of adults who sought healthcare for respiratory illness found that those who had received the 2025–2026 COVID vaccine were 59 percent less likely to develop symptomatic COVID requiring a healthcare visit than those who had not received the updated vaccine, a finding that covers the first two months after vaccination.