The ACT has recorded two cases of monkeypox, the first to be detected in Canberra.
ACT Health said both people had recently travelled from Europe and were isolating at home with mild symptoms.
A spokesperson for the directorate said the transmission risk to others in the community was low.
"ACT Health is continuing to undertake contact tracing," the spokesperson said in a statement.
"No high-risk contacts have been identified."
Monkeypox is a rare but potentially serious viral illness spread person-to-person via close contact.
Infection needs to be confirmed by testing the blister fluid or scabs from the skin rash.
ACT Chief Health Officer Kerryn Coleman said illness association with monkeypox was "usually mild", but that sometimes complications could occur.
"Following these symptoms, a rash usually develops, that spreads to other parts of the body. The rash changes and goes through stages, like chickenpox, before finally becoming a scab."
Monkeypox was previously associated with travel to Central and West Africa, but has already been detected in other parts of the world, including Australia.
Queensland Health confirmed its first case of the illness two days ago.
And last week, NSW health authorities urged people to be aware of the symptoms of monkeypox after the likely transmission of the virus in that state.
At least 11 cases have been detected there, nine of them likely acquired overseas.
