The year was 1957, the game show was called "I've Got A Secret" and the guest had a most mysterious and ominous name: Dr. X.
Since the premise of "I've Got A Secret" was that contestants had to guess an unknown fact about the show's guests (Dr. X was joined that night by a popular comedian, Buster Keaton), the contestants immediately probed Dr. X for details. When one of them asked if he invented a machine that is painful when used, the soft-spoken Dr. X cracked up the audience by replying, "Yes, sometimes it's most painful."
