The Tunisian Football Federation fired national team coach Mondher Kebaier on Sunday following a quarterfinal exit at the African Cup of Nations.
He was replaced by his assistant, Jalel Kadri, the federation said.
Kadri will oversee the team in a World Cup qualifying playoff against Mali in March.
Tunisia beat Nigeria in the last 16 at the African Cup in Cameroon to raise hopes of a strong challenge this year. However, it lost 1-0 to Burkina Faso in the quarterfinals on Saturday.
Ultimately it was a poor African Cup for the 2004 champion after losing group games to Mali and tournament debutant Gambia and only qualifying for the knockout stage as one of the best third-place teams.
The 50-year-old Kadri has an opportunity to avenge the defeat to Mali when the teams meet again in the two-leg World Cup playoff.