There's more travel misery ahead for millions of people with staff at 13 rail companies staging mass walkouts on Wednesday.
They will strike tomorrow with the long-running dispute over pay, jobs and conditions still no closer to a resolution.
The deadlock means that once again the UK will be plunged into commuter chaos, days on from the weekend's industrial action which caused widespread frustration across Britain.
The disgruntled train drivers' strike will affect: Avanti West Coast, Chiltern, CrossCountry, East Midlands Trains, Greater Anglia, Great Western, Hull Trains and LNER.
The walk-out will also affect the London Overground, Northern Trains, Southeastern, Transpennine Express and West Midlands Trains.
Members of the drivers' union Aslef and the Transport Salaried Staffs Association TSSA will strike, causing huge disruption to services.
Aslef general secretary Mick Whelan says the dispute would now continue until the Government intervened.
He urged Transport Secretary Anne-Marie Trevelyan to "lift the shackles" from train companies so they could make a pay offer to workers.
"The message I am receiving from my members is that they are in this for the long haul and if anything they want industrial action to be increased," he said.
Members of the TSSA will strike at CrossCountry and take other forms of industrial action at several other operators.
The TSSA is also planning industrial action on Thursday, Friday and Saturday, while members of the Rail, Maritime and Transport union at more than a dozen train companies and Network Rail will strike on Saturday.
Passengers are advised to check before they travel on Wednesday and allow extra time for their journey.
Train companies not involved in the strike will be running trains, but these are expected to be busy.
Services are likely to be disrupted in the early morning of Thursday as workers return to duties.
The disruption will affect football fixtures and the final day of the Conservative Party conference in Birmingham.
Daniel Mann, director of industry operations at the Rail Delivery Group, said: "These strikes disrupt the travel plans of millions of passengers and undermine businesses who continue to struggle with rising costs and this continued action will only further damage the railway's recovery.
"While some rail companies are not involved in the strike, services are likely to be busy, severely disrupted or in some cases not running, so passengers should check the latest travel advice before setting off.
"Passengers with advance, off-peak or anytime tickets affected by the strikes on October 5 can use their ticket on the day before the booked date, or up to and including October 7.
"Passengers can also change their tickets to travel on an alternate date or get a refund if their train is cancelled or rescheduled."