Lorena Wiebes (SD Worx-Protime) won stage 1 and secured the first yellow jersey of this Tour de France Femmes, proving her resilience by sprinting to victory atop the Côte Saint-François, which split the peloton. Several bike lengths back, Kim Le Court-Pienaar (AG Insurance-Soudal) took second place, followed by Demi Vollering (FDJ United-Suez) in third place.
A breakaway of four got a large gap early on the stage, and Océane Mahé (Ma Petite Entreprise) took enough mountain points to take the polka-dot jersey, dropping back after the Côte de Vuillens, where Nikola Nosková (Cofidis) went solo, just over 40km from the finish.