Ryan Sessegnon has joined Oliver Skipp on the sidelines for Tottenham’s visit to Manchester United in a fresh blow for Antonio Conte.
Sergio Reguilon, who scored with his first touch in Monday’s 5-0 win over Everton, comes in at left wing-back but Conte has a largely settled side apart from that.
Rodrigo Bentancur partners Pierre-Emile Hojbjerg in midfield, while Matt Doherty keeps his place on the right.
Conte was mooted as a possible United boss before he joined Spurs but he says he was unaware of the interest and already happily committed to Spurs.
“Honestly, I think that when United decided to sack Solskjaer, I had signed for Tottenham,” Conte said.
“I enjoyed to do this, because at that moment, I found this situation very good for me, to work in modern club with fantastic stadium and training ground, with a big task to try to build something important, to build something competitive for the future.
“And then I signed for Tottenham, it happened after I signed. But honestly, I was very focused, and I am so focused on the Tottenham job, that I didn’t read this. I didn’t read this. The present is Tottenham, for me. I am enjoying a lot to work with this club, with these players, we are trying to improve, to raise our level, this is my target in this moment. I repeat: I am enjoying doing it.”
Tottenham XI (3-4-3): Lloris; Romero, Dier, Davies; Doherty, Bentancur, Hojbjerg, Reguilon; Kulusevski, Son, Kane.
Subs: Gollini, Rodon, Sanchez, Royal, White, Winks, Bergwijn, Lucas, Scarlett
Where: Old Trafford, Manchester
When: Saturday, March 12, 17.30
TV: Sky Sports
Referee: Jonathan Moss
