Chelsea owner Todd Boehly thanked Marina Granovskaia for her "many years of excellent service" as he unveiled the Blues' new hierarchy.
The American tycoon, 48, will become interim sporting director as the highly-regarded Granovskaia departs Stamford Bridge after 19 years. Boehly completed his takeover of the West London club in late May to end months of uncertainty under his predecessor, Roman Abramovich.
Accompanying a statement released on the club's official website on Wednesday morning, Boehly said: "As custodians of Chelsea FC, we now begin executing our long-term vision and plan for the Club, creating an outstanding experience for its passionate, loyal fans, and continuing to challenge for top honours in line with Chelsea FC's decorated history.