There's a real thing for '90s cartoon aesthetics in game art lately, from Rain98 to Being Food. Yet none has taken that inspiration in a direction that's quite so... visceral. Oh, My Doug is an upcoming metroidvania set inside the body of a very unhealthy middle-aged man.
The game features very weird scenarios: you'll be able to chat with a talking sperm cell and wander a cemetery in your host's bowels. There are weird weapons, and everything is drawn by hand and animated frame-by-frame.