‘There has never been a more dangerous time to take drugs’: the rising global threat of nitazenes and synthetic opioids

US Drug Enforcement Administration images accompanying a warning about the emergence of nitazenes in Washington DC, June 2022 USDEA

In the early hours of September 14 2021, three men parked in a quiet car park in the southern English market town of Abingdon-on-Thames. The men, returning from a night out, had pulled over to smoke heroin.

Unknown to them, the drug had been fortified with a nitazene compound called isotonitazene, a highly potent new synthetic opioid. Two of the men, Peter Haslam and Adrian Davies, overdosed and went into cardiac arrest. The third, Michael Parsons, tried to save them and himself by injecting naloxone, an opioid overdose antidote. Despite paramedics also trying to resuscitate Haslam and Davies, both died at the scene.