People who often experience overwhelming fatigue, unrefreshing sleep, cognitive difficulties, pain, and a variety of autonomic and sensory disturbances may be suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). It's a complex, long-term, chronic illness that affects multiple body systems and significantly reduces a person's ability to function. A defining feature of ME/CFS is post-exertional malaise, a worsening of symptoms after even minor physical or mental activity. In the United States, millions are estimated to live with ME/CFS, with many facing periods of being homebound or even bedbound due to the severity of their symptoms.
In response to this landscape, the Solve ME/CFS Initiative (Solve M.E.) has positioned itself as a catalyst for research and policy engagement. It also leads community-centered data efforts to advance diagnostics, treatments, and understanding of ME/CFS, Long COVID, and related post-infectious conditions.
