In 2004, Mario Cibelli was preparing a 75-year-old patient for a big cardiac operation when the patient’s daughter asked for a quick word. “She explained to me how worried she was about the surgery,” says Cibelli, a consultant in anaesthesia and intensive care at the University Hospitals Birmingham. “I said: ‘Look, everybody’s worried about heart surgery, it comes with risks, but normally people benefit from it.’ And then she told me that her father had undergone a cardiac procedure two years before and he had changed dramatically.”
Cibelli listened as the woman described how her father, a former physics professor, had shown signs of significant cognitive decline after the initial operation. Once a keen chess player, he was now unable to play the game and struggled to even do basic crosswords.
