The chemical imbalance theory of depression is well and truly dead. A paper by Joanna Moncrieff and colleagues, long-time critics of the effectiveness of antidepressants, has caused a splash. The paper provides a summary of other summaries that confirm there is no evidence to support the idea that depression is caused by disturbance of the brain’s serotonin system.
They have done us a favour by corralling the evidence that says as much, even if we already knew this to be the case.
