Supergirl crash-landed in 2025's Superman, and now she's back with her own solo film: a suitably grittier, edgier, and rougher second entry in the DCU that puts Milly Alcock's Kara Zor-El on a quest through space to save her dog, Krypto, from a vicious poison.
The trouble begins when sadistic brigand Krem (a near-unrecognizable Matthias Schoenaerts) callously shoots Krypto with a poisoned dart, after slaughtering the family of Ruthye (Eve Ridley), setting the youngster on a revenge mission that leads to her path crossing with Kara's. Since we saw her reclaim Krypto in Superman, Kara has been drinking her way across the galaxy, enjoying the benefits of a red sun (which strips her of her powers), and ignoring calls from her cousin, one Clark Kent, urging her to return to Earth so she can find her feet on the planet.