A multi-institutional study led by researchers from St. John's Research Institute has found that BCG revaccination of young adults can boost the immune efficacy of Covishield vaccine.
Published last week in Frontiers in Immunology, a peer-reviewed journal, this study provides the first in-depth analysis of immune responses to Covishield, the first and most widely distributed COVID-19 vaccine in India.
BCG vaccine is routinely administered in many countries at birth. When given for the second time in young adults, this group of researchers previously showed that it could boost immune responses targeting genes expressed by Mycobacterium tuberculosis (the causative agent of TB) without any adverse effects.