Exeter Chiefs' star centre Henry Slade has recovered injury to be named in England’s 36-man squad for Sunday's Guinness Six Nations clash with Italy at Twickenham.
The centre was ruled out of the 29-23 defeat to Scotland on Saturday after sustaining a hip problem while on club duty.
London Irish winger Henry Arundell also returns to the squad having recovered from a foot injury which kept the 20-year-old out of action from October through to the end of January when he made his playing return for the Exiles who are in Premiership Rugby Cup semi-final action on Friday night against Northampton Saints.
Exeter Chiefs host Sale Sharks in the other semi-final on Sunday.
England vice-captain Courtney Lawes will also be in camp once again as the Northampton Saints forward continues rehabilitation work from a calf injury.
Harlequins winger Cadan Murley and Leicester centre Guy Porter miss out this week having been involved ahead of Steve Borthwick's first game as England manager after replacing Eddie Jones as head coach in December.
Kieran Crowley’s Italy opened their campaign with a 29-24 defeat to defending champions France in Rome on Sunday.
FULL SQUAD
FORWARDS
Ollie Chessum (Leicester Tigers, 6 caps)
Dan Cole (Leicester Tigers, 96 caps)
Ben Curry (Sale Sharks, 2 caps)
Alex Dombrandt (Harlequins, 10 caps)
Tom Dunn (Bath Rugby, 3 caps)
Ben Earl (Saracens, 14 caps)
Ellis Genge (Bristol Bears, 44 caps)
Jamie George (Saracens, 73 caps)
Joe Heyes (Leicester Tigers, 7 caps)
Jonny Hill (Sale Sharks, 19 caps)
Nick Isiekwe (Saracens, 9 caps)
Maro Itoje (Saracens, 63 caps)
Lewis Ludlam (Northampton Saints, 15 caps)
David Ribbans (Northampton Saints, 3 caps)
Bevan Rodd (Sale Sharks, 2 caps)
Sam Simmonds (Exeter Chiefs, 18 caps)
Kyle Sinckler (Bristol Bears, 57 caps)
Mako Vunipola (Saracens, 75 caps)
Jack Walker (Harlequins, uncapped)
Jack Willis (Toulouse, 6 caps)
BACKS
Henry Arundell (London Irish, 3 caps)
Owen Farrell (Saracens, 102 caps)
Tommy Freeman (Northampton Saints, 3 caps)
Ollie Hassell-Collins (London Irish, 1 cap)
Ollie Lawrence (Bath Rugby, 8 caps)
Max Malins (Saracens, 15 caps)
Joe Marchant (Harlequins, 14 caps)
Alex Mitchell (Northampton Saints, 1 cap)
Henry Slade (Exeter Chiefs, 52 caps)
Fin Smith (Northampton Saints, uncapped)
Marcus Smith (Harlequins, 18 caps)
Freddie Steward (Leicester Tigers, 18 caps)
Manu Tuilagi (Sale Sharks, 50 caps)
Jack van Poortvliet (Leicester Tigers, 8 caps)
Anthony Watson (Leicester Tigers, 52 caps)
Ben Youngs (Leicester Tigers, 122 caps)
