With the exception of Superman and Batman, no comic book character has had the kind of recurring cinematic success that Spider-Man has. In just 24 years, Stan Lee and Steve Ditko’s most famous creation has appeared in eight live-action films (plus MCU guest appearances) and gone through three reboots, not to mention a host of animated projects and TV shows. Part of that success is due to Spider-Man’s longevity on the page, which has given him 65 years of intricate comic book canon to explore on-screen.
So far, the MCU has strayed away from direct adaptations of specific storylines (except for loosely introducing the concept of the Spider-Verse), instead preferring to remix them or go with original plotlines featuring classic villains tailored for Marvel’s cinematic universe. The Vulture ended up being an aggrieved blue-collar cleanup worker, Mysterio sold himself to Peter as a reality-hopping hero, and the villains of No Way Home aren’t multiversal vampires but an interdimensional version of the Sinister Six.