South Park was incredibly on the nose with many of the jokes directed at Prince Harry and Meghan Markle - but only eagle-eyed viewers spotted one relating to Michelle Obama.
Everything from Harry's frostbitten todger to Meghan's many magazine covers was covered by show creators Trey Parker and Matt Stone, who left no stone unturned.
The Duke and Duchess of Sussex weren't named directly, instead their cartoon versions were under the guise of the fictional Prince and Princess of Canada.
After going on their 'Worldwide Privacy Tour', the royal couple then headed to a PR agency so they could improve their brand.
Once there, we got a glimpse of the Meghan character's profile on the database, which listed her roles as being a "sorority girl, actress, influencer and victim".
The Harry cartoon character then got told he must be the "royal prince, millionaire, world traveller victim".
On the profile for the princess, it listed her interests as yoga, calligraphy, cuisine, writing, lifestyle, advocating, acting, blogging and feminism.
But they managed to slip in some very cheeky ones, including 'lawyer pretending' and 'First Lady Botherer'.
The former is obviously a reference to the former actress being in Suits, while the latter is the insinuation she is bothering Michelle Obama.
Harry, Michelle and her husband, former US president Barack Obama, seemingly forged a close working relationship - and appeared together in an unforgettable video to promote the 2016 Invictus Games.
When Harry wed Meghan it was said that his new wife and ex-first lady also bonded over shared interests.
Meghan was said to have had a 'power meeting' with Michelle in London as the former first lady promoted her autobiography, Becoming - with the pair reportedly having a "long private audience" afterwards.
A friend told the Evening Standard : "They spoke at length about the importance of supporting and empowering women across all cultures and communities.
"They also talked about shared experiences of pregnancy and raising children, plus shared causes including girls’ education."
However, according to the book Revenge: Meghan, Harry and the War Between the Windsors by Tom Bower, Michelle was "alarmed" by Meghan's attitude when she was attempting to find her royal role.
The book says the former first lady said in an interview about Meghan: "Take some time and don’t be in a hurry to do anything."
Bower adds: "In a warning note, she added: 'Like me, Meghan probably never dreamt she’d have a life like this; no-deal, the pressure you feel can sometimes feel like a lot.’
"Meghan, Obama suggested, should be reasonable: ‘What I’d say is that there’s so much opportunity to do good with a platform like that and I think Meghan can maximise her impact for others, as well her own happiness, if she’s doing something that resonates with her personally'."
Michelle also spoke about Harry and Meghan's bombshell interview with Oprah Winfrey.
In an interview with NBC, Mrs Obama was asked what she thought of Meghan telling Oprah she had "experienced racism".
She said: "The thing I hope for and the thing that think about is that this is first and foremost is a family and I pray for forgiveness and healing for them so they can use this as a teachable moment for us all."
royal insiders suggested the former presidential couple were being cautious about appearing friendly with Harry and Meghan due to concerns about public image and out of respect for the Queen - who they are known to greatly admire.
Harry's well-publicised attacks on his royal relatives soured the Obama's opinion of the couple, according to an article written by royal expert Camilla Tominey in the Telegraph.
Camilla said: "It arguably will not have gone down well with a couple who have always put 'family first' to see Harry and Meghan being so openly critical of their royal relatives during their Oprah interview in March."
Meanwhile, an insider told her: "The Obamas didn’t like Harry attacking his family. They value family and certainly aren’t the type of people who would want their children talking to the press."
Interestingly, a comparison between the Sussexes and the Obamas was made on American broadcaster Megyn Kelly's show.
The American journalist said any hopes that the former Suits actress and her husband may have had for a career in politics have now been "dashed."
"You know it’s bad when your PR tour lands you a little skit, a great skit, on South Park," the 52-year-old said on the latest episode of her hit podcast the Megyn Kelly Show.
"They have jumped the shark, they are not beloved and her hopes of running for president, reported hopes, are all but dashed. When ‘South Park’ turns on you, there’s no recovering."
Ms Kelly's guest, National Review's Michael Brendan Dougherty, agreed that any hopes the California-based royals had of becoming the next Barack and Michelle Obama are now over.
"The whole result of their giant publicity campaign has been to raise the popularity of Prince William and Kate," Mr Dougherty said.
"Now they're just so cringeworthy and so unsympathetic in a fundamental way that they are of no use to anyone but their overpaid publicists and the kind of grifters trying to sell kitsch attached to their names."
The portrayal of the Sussexes on the TV show has reportedly "upset and overwhelmed" Meghan over the last few days, according to a The Spectator source.
The insider also added that the duchess "is annoyed by South Park but refuses to watch it all".
One royal commentator has claimed that the couple "could call in the lawyers" against the hit-Comedy Central show.
Neil Sean told Fox News: "According to sources close to the ex-royals, it appears that, like so many things with Meghan and Harry, this may have legal ramifications attached.
"Their legal team are casting an eye over the episode to see what is wrong, and what could be turned into something more sinister."