Wales need to beat South Africa in Bloemfontein this weekend to level things at 1-1 and set up a gripping final Test decider.
Has the Springboks' selection of a second-string side played into Welsh hands? Gareth Edwards certainly appears to think it should. Will we finally see a first Wales triumph on South African soil?
Our expert writers gaze into their crystal balls and give their predictions:
Matthew Southcombe: Pivac's men to just nick it and make history
Last weekend was a decent opportunity for Wales. South Africa were clearly heading into the first Test having not played together for quite a while. Wales did indeed catch the world champions cold but blew an 18-3 half-time lead. That hurt this week and the debrief will not have been pleasant.
Springbok boss Jacques Nienaber has given Wales another decent chance though, making wholesale changes for the second Test in Bloemfontein. His side is stacked with United Rugby Championship finalists and players who have been in brilliant form this season, but a number of combinations are unfamiliar and it may take some time to settle.
There is a lot of the unknown about this South Africa side, which makes it very difficult to predict what is going to happen. Really, though, Wales should be viewing this as a great opportunity.
Pivac has gone for consistency and the players will be better for last week's performance. Wales are typically slow starters in campaigns but they were impressive in Pretoria and are building from a more solid foundation in this series than they usually do.
If they play to their potential, they should have too much for an inexperienced 'Bok team, even though, as mentioned, it is full of in-form players. Wales are all guns blazing and stacked with their strongest possible XV. Like last week, this is a great chance to claim a historic victory on South African soil.
South Africa 27 - 30 Wales
Mark Orders: Home advantage to sway nip and tuck clash
What can Wales do about South Africa’s bold call to make 14 changes?
Give them a good tonking, suggested Gareth Edwards. If only Pivac’s team had the great man in his prime playing for them this weekend. Let’s see what happens.
The side South Africa are putting out is still dangerous, with power up front and pace behind. The two props are strong scrummagers, Eben Etzebeth features once again, the back row bristles with quality, Andre Esterhuizen is one of the most powerful centres in the world and there is speed to spare in the back three.
That said, Wales have an opportunity because despite the impressive names on the Boks’ team-sheet, games are not won on paper and shaken-up teams don’t always gel.
The tourists will miss the injured Tomas Francis, their best scrummaging tighthead, with Wales now covering Dillon Lewis, himself renowned more for his work around the field than at the set-piece, with a youngster in Sam Wainwright who isn’t a regular at his club.
Will Pivac’s side have the courage to use their backs more? Or will they look to keep the frills locked away and play in Springbok faces, doing all they can to disrupt and frustrate? Probably the latter, on the basis that it worked to a degree last week and if it ain’t broke then why fix it?
Wales should take a lot of confidence from their gutsy effort in the series opener, but had they prevailed at Loftus Versfeld their belief levels would have been topped up even more.
While no-one will be quick to write Wales off, the Springboks are favourites. There may not be much in it, but home advantage and momentum count for a lot, and South Africa’s bench is strong, even if many of the faces have changed from last week.
South Africa 34-28 Wales
What do you think the second Test result will be? Have your say in the comments section here.
Ben James: Match last week's intensity and Wales will win
Before this summer tour, South Africa's selection policy could only be described as consistent, while Wales' was anything but. The Springboks know their plan perfectly and won't stray from it, while Pivac's side has undergone numerous personnel changes in the search for a winning formula.
That is what makes this weekend's Test so intriguing. The Springboks, despite what Jacques Nienaber had suggested before the tour, have made a raft of changes by ripping up last week's side to name a new-look 23 full of individual talent.
As for Pivac, he has opted not to make sweeping changes. Alex Cuthbert comes in for Josh Adams, Wyn Jones makes the bench and Tomas Francis is obviously missing, but otherwise it is all the same.
South Africa's decision to roll the dice versus Wales' resolution for more of the same. Two relative novelties in recent times, making it all the harder to forecast how things will turn out.
The Springboks' team is full of in-form players, with one international player remarking to me earlier this week that it is boasting more individual threats with the ball. If their backline clicks, it might be a tough evening for Wales.
But cohesiveness, or a lack of it, could be the Springboks' downfall. If Wales can match last week's intensity and repair some discipline issues, then maybe, just maybe, they can finally get over the line in South Africa.
South Africa 23-25 Wales
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Wayne Pivac Q&A: Why I like Alex Cuthbert so much and the kid who has a huge future
The verdict on the Wales team as bulldozer making such an impact he's being kept on bench
