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The Guardian - UK
The Guardian - UK
Business
Julia Kollewe

Small wonder: big DNA advances loom at university startup Oxford Nanopore

Dr Gordon Sanghera, CEO, shows off the small Oxford Nanopore DNA/RNA sequencing device.
Dr Gordon Sanghera, CEO, shows off the small Oxford Nanopore DNA/RNA sequencing device. Photograph: Graeme Robertson/The Guardian

Not far from Didcot, once a halfway stop between London and Bristol on the Great Western Railway celebrated for Isambard Kingdom Brunel’s engineering, innovation has returned with a hi-tech factory manufacturing DNA and RNA sequencing machines.

Oxford Nanopore, a spinout from Oxford University, produces devices used to identify viruses and spot variants in the genetic makeup of humans, animals and plants. Its sequencers have been used to track Covid-19 variants globally and are now being trialled on intensive care patients with respiratory infections at Guy’s and St Thomas’ hospitals in London, and in the fight against the 200 drug-resistant strains of tuberculosis, the second-biggest killer worldwide after Covid in 2020.

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